We have, at long last, written a guide showing why and how to use Guix (and Software Heritage) for reproducible computational experiments and how to refer to it in a paper:
https://hpc.guix.info/blog/2023/06/a-guide-to-reproducible-research-papers/
The guide includes step-by-step instructions that should make the whole process more approachable.
We’ll be running a reproducible research hackathon on June 27th, in connection with the ReScience C journal—an opportunity to put this guide to good use!